Flunitrazepam (pronounced /ˌfluːnɨˈtræzɨpæm/) is marketed as a hypnotic drug and has sedative, anticonvulsant, anxiolytic, amnestic, hypnotic and skeletal muscle relaxant properties. A short-intermediate acting benzodiazepine derivative, flunitrazepam is prescribed for the treatment of severe insomnia, marketed by Roche most commonly under the trade name Rohypnol (informally Rufinol) -also marketed in some countries under the trade names Hipnosedon, Hypnodorm, Flunipam, Nilium, Vulbegal, Silece, Darkene, Ilman and Insom.
The prescription of flunitrazepam as a hypnotic is generally intended to be for short-term treatment of chronic, or severe insomnias that are not responsive to other hypnotics, especially in inpatients. It is considered to be one of the most effective benzodiazepine hypnotics on a dose basis.
Just as with other hypnotics, flunitrazepam should only be used on a short term basis or in those with chronic insomnia on an occasional basis.
The drug is sometimes used as a date rape drug (commonly referred to in street slang as a “roofie“).
Flunitrazepam is classed as a nitrobenzodiazepine. It was developed by combining nitrazepam with fluorine. Other nitrobenzodiazepines include nitrazepam and clonazepam.
The Dutch, British and French use a system called the System of Objectified Judgement Analysis for assessing whether drugs should be included in drug formularies based on clinical efficacy, adverse effects, pharmacokinetic properties, toxicity and drug interactions. A Dutch analysis using the system found that flunitrazepam is unsuitable to be included in drug prescribing formularies.
Rohypnol is the brand name for a drug called Flunitrazepam, which is a powerful sedative that depresses the central nervous system. Rohypnol is not legally available for prescription in the United States, but is legal in 60 countries worldwide for treatment of insomnia.Cigarette manufacturers provide now tobacco available on the online cigarettes shop without paying "convenience" store prices. Cigarettes like other tobacco products do carry health effects with them. Most modern manufactured cigarettes are filtered and include tobacco.